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genechip human genome u133 plus 2.0 microarray platform  (Thermo Fisher)


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    Thermo Fisher genechip human genome u133 plus 2.0 microarray platform
    Genes associated with oxidative phosphorylation (mitochondria function). a Enrichment plot of KEGG_Oxidative phosphorylation gene set identified by GSEA. Middle section (black bars) illustrate the position of the genes belonging to the gene set in the context of all the genes on the Affymetrix <t>U133</t> plus 2.0 array. The enrichment score (ES) plotted as a function of the position within the ranked list of array genes is shown as a green line. The ranked list metric shown in gray illustrates the correlation between the signal to noise values of all individually ranked genes according to the neutrophil samples of the ‘before’ and ‘after’ tocilizumab treatment (experimental conditions). b on the left is GSEA-derived heat map of the 110 leading edge genes that correlates with response to tocilizumab and contributing to the enrichment score; on the right is the top 20 genes that includes some of the genes mapped by IPA to mitochondria dysfunction pathway (in red asterisks). Signal intensities are illustrated by varying shades of red (increased) and blue (decreased). c Quantitative real-time polymerase chain reaction (qRT-PCR) validation of differentially expressed genes ( NDUFB2 , COX6C , LAT ) observed in this microarray experiment. The relative fold change of both microarray (solid bar) and qRT-PCR (open bars) are shown. The data for qRT-PCR are the average of 3 independent experiments done on the same sample
    Genechip Human Genome U133 Plus 2.0 Microarray Platform, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/genechip+human+genome+u133+plus+2%2E0+microarray+platform/pmc04746827-32-11-10?v=Thermo+Fisher
    Average 90 stars, based on 1 article reviews
    genechip human genome u133 plus 2.0 microarray platform - by Bioz Stars, 2026-07
    90/100 stars

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    1) Product Images from "Mitochondrial and oxidative stress genes are differentially expressed in neutrophils of sJIA patients treated with tocilizumab: a pilot microarray study"

    Article Title: Mitochondrial and oxidative stress genes are differentially expressed in neutrophils of sJIA patients treated with tocilizumab: a pilot microarray study

    Journal: Pediatric Rheumatology Online Journal

    doi: 10.1186/s12969-016-0067-7

    Genes associated with oxidative phosphorylation (mitochondria function). a Enrichment plot of KEGG_Oxidative phosphorylation gene set identified by GSEA. Middle section (black bars) illustrate the position of the genes belonging to the gene set in the context of all the genes on the Affymetrix U133 plus 2.0 array. The enrichment score (ES) plotted as a function of the position within the ranked list of array genes is shown as a green line. The ranked list metric shown in gray illustrates the correlation between the signal to noise values of all individually ranked genes according to the neutrophil samples of the ‘before’ and ‘after’ tocilizumab treatment (experimental conditions). b on the left is GSEA-derived heat map of the 110 leading edge genes that correlates with response to tocilizumab and contributing to the enrichment score; on the right is the top 20 genes that includes some of the genes mapped by IPA to mitochondria dysfunction pathway (in red asterisks). Signal intensities are illustrated by varying shades of red (increased) and blue (decreased). c Quantitative real-time polymerase chain reaction (qRT-PCR) validation of differentially expressed genes ( NDUFB2 , COX6C , LAT ) observed in this microarray experiment. The relative fold change of both microarray (solid bar) and qRT-PCR (open bars) are shown. The data for qRT-PCR are the average of 3 independent experiments done on the same sample
    Figure Legend Snippet: Genes associated with oxidative phosphorylation (mitochondria function). a Enrichment plot of KEGG_Oxidative phosphorylation gene set identified by GSEA. Middle section (black bars) illustrate the position of the genes belonging to the gene set in the context of all the genes on the Affymetrix U133 plus 2.0 array. The enrichment score (ES) plotted as a function of the position within the ranked list of array genes is shown as a green line. The ranked list metric shown in gray illustrates the correlation between the signal to noise values of all individually ranked genes according to the neutrophil samples of the ‘before’ and ‘after’ tocilizumab treatment (experimental conditions). b on the left is GSEA-derived heat map of the 110 leading edge genes that correlates with response to tocilizumab and contributing to the enrichment score; on the right is the top 20 genes that includes some of the genes mapped by IPA to mitochondria dysfunction pathway (in red asterisks). Signal intensities are illustrated by varying shades of red (increased) and blue (decreased). c Quantitative real-time polymerase chain reaction (qRT-PCR) validation of differentially expressed genes ( NDUFB2 , COX6C , LAT ) observed in this microarray experiment. The relative fold change of both microarray (solid bar) and qRT-PCR (open bars) are shown. The data for qRT-PCR are the average of 3 independent experiments done on the same sample

    Techniques Used: Derivative Assay, Real-time Polymerase Chain Reaction, Quantitative RT-PCR, Microarray



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    Thermo Fisher genechip human genome u133 plus 2.0 microarray platform
    Genes associated with oxidative phosphorylation (mitochondria function). a Enrichment plot of KEGG_Oxidative phosphorylation gene set identified by GSEA. Middle section (black bars) illustrate the position of the genes belonging to the gene set in the context of all the genes on the Affymetrix <t>U133</t> plus 2.0 array. The enrichment score (ES) plotted as a function of the position within the ranked list of array genes is shown as a green line. The ranked list metric shown in gray illustrates the correlation between the signal to noise values of all individually ranked genes according to the neutrophil samples of the ‘before’ and ‘after’ tocilizumab treatment (experimental conditions). b on the left is GSEA-derived heat map of the 110 leading edge genes that correlates with response to tocilizumab and contributing to the enrichment score; on the right is the top 20 genes that includes some of the genes mapped by IPA to mitochondria dysfunction pathway (in red asterisks). Signal intensities are illustrated by varying shades of red (increased) and blue (decreased). c Quantitative real-time polymerase chain reaction (qRT-PCR) validation of differentially expressed genes ( NDUFB2 , COX6C , LAT ) observed in this microarray experiment. The relative fold change of both microarray (solid bar) and qRT-PCR (open bars) are shown. The data for qRT-PCR are the average of 3 independent experiments done on the same sample
    Genechip Human Genome U133 Plus 2.0 Microarray Platform, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/genechip+human+genome+u133+plus+2%2E0+microarray+platform/pmc04746827-32-11-10?v=Thermo+Fisher
    Average 90 stars, based on 1 article reviews
    genechip human genome u133 plus 2.0 microarray platform - by Bioz Stars, 2026-07
    90/100 stars
      Buy from Supplier

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    Thermo Fisher genechip (r) human genome u133 plus 2.0 microarray platform
    Genes associated with oxidative phosphorylation (mitochondria function). a Enrichment plot of KEGG_Oxidative phosphorylation gene set identified by GSEA. Middle section (black bars) illustrate the position of the genes belonging to the gene set in the context of all the genes on the Affymetrix <t>U133</t> plus 2.0 array. The enrichment score (ES) plotted as a function of the position within the ranked list of array genes is shown as a green line. The ranked list metric shown in gray illustrates the correlation between the signal to noise values of all individually ranked genes according to the neutrophil samples of the ‘before’ and ‘after’ tocilizumab treatment (experimental conditions). b on the left is GSEA-derived heat map of the 110 leading edge genes that correlates with response to tocilizumab and contributing to the enrichment score; on the right is the top 20 genes that includes some of the genes mapped by IPA to mitochondria dysfunction pathway (in red asterisks). Signal intensities are illustrated by varying shades of red (increased) and blue (decreased). c Quantitative real-time polymerase chain reaction (qRT-PCR) validation of differentially expressed genes ( NDUFB2 , COX6C , LAT ) observed in this microarray experiment. The relative fold change of both microarray (solid bar) and qRT-PCR (open bars) are shown. The data for qRT-PCR are the average of 3 independent experiments done on the same sample
    Genechip (R) Human Genome U133 Plus 2.0 Microarray Platform, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/genechip+human+genome+u133+plus+2%2E0+microarray+platform/pmc05350776-4349-12-11?v=Thermo+Fisher
    Average 90 stars, based on 1 article reviews
    genechip (r) human genome u133 plus 2.0 microarray platform - by Bioz Stars, 2026-07
    90/100 stars
      Buy from Supplier

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    Genes associated with oxidative phosphorylation (mitochondria function). a Enrichment plot of KEGG_Oxidative phosphorylation gene set identified by GSEA. Middle section (black bars) illustrate the position of the genes belonging to the gene set in the context of all the genes on the Affymetrix U133 plus 2.0 array. The enrichment score (ES) plotted as a function of the position within the ranked list of array genes is shown as a green line. The ranked list metric shown in gray illustrates the correlation between the signal to noise values of all individually ranked genes according to the neutrophil samples of the ‘before’ and ‘after’ tocilizumab treatment (experimental conditions). b on the left is GSEA-derived heat map of the 110 leading edge genes that correlates with response to tocilizumab and contributing to the enrichment score; on the right is the top 20 genes that includes some of the genes mapped by IPA to mitochondria dysfunction pathway (in red asterisks). Signal intensities are illustrated by varying shades of red (increased) and blue (decreased). c Quantitative real-time polymerase chain reaction (qRT-PCR) validation of differentially expressed genes ( NDUFB2 , COX6C , LAT ) observed in this microarray experiment. The relative fold change of both microarray (solid bar) and qRT-PCR (open bars) are shown. The data for qRT-PCR are the average of 3 independent experiments done on the same sample

    Journal: Pediatric Rheumatology Online Journal

    Article Title: Mitochondrial and oxidative stress genes are differentially expressed in neutrophils of sJIA patients treated with tocilizumab: a pilot microarray study

    doi: 10.1186/s12969-016-0067-7

    Figure Lengend Snippet: Genes associated with oxidative phosphorylation (mitochondria function). a Enrichment plot of KEGG_Oxidative phosphorylation gene set identified by GSEA. Middle section (black bars) illustrate the position of the genes belonging to the gene set in the context of all the genes on the Affymetrix U133 plus 2.0 array. The enrichment score (ES) plotted as a function of the position within the ranked list of array genes is shown as a green line. The ranked list metric shown in gray illustrates the correlation between the signal to noise values of all individually ranked genes according to the neutrophil samples of the ‘before’ and ‘after’ tocilizumab treatment (experimental conditions). b on the left is GSEA-derived heat map of the 110 leading edge genes that correlates with response to tocilizumab and contributing to the enrichment score; on the right is the top 20 genes that includes some of the genes mapped by IPA to mitochondria dysfunction pathway (in red asterisks). Signal intensities are illustrated by varying shades of red (increased) and blue (decreased). c Quantitative real-time polymerase chain reaction (qRT-PCR) validation of differentially expressed genes ( NDUFB2 , COX6C , LAT ) observed in this microarray experiment. The relative fold change of both microarray (solid bar) and qRT-PCR (open bars) are shown. The data for qRT-PCR are the average of 3 independent experiments done on the same sample

    Article Snippet: RNA was extracted and gene expression profiling was performed using Affymetrix GeneChip Human Genome U133 Plus 2.0 microarray platform.

    Techniques: Derivative Assay, Real-time Polymerase Chain Reaction, Quantitative RT-PCR, Microarray